Article
Influence of Smoking Status and Intensity on Discovery of Blood Pressure Loci Through Gene-Smoking Interactions.
Genetic epidemiology - 1 Sept 2015
Basson Jacob, Sung Yun Ju, de las Fuentes Lisa, Schwander Karen, Cupples L Adrienne, Rao D C
Abstract excerpt
BACKGROUND: Genetic variation accounts for approximately 30% of blood pressure (BP) variability but most of that variability has not been attributed to specific variants. Interactions between genes and BP-associated factors may explain some "missing heritability." Cigarette smoking increases BP after short-term exposure and decreases BP with longer exposure. Gene-smoking interactions have discovered novel BP...
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