Article
Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes.
Journal of autoimmunity - 1 Jun 2015
Tomer Yaron, Dolan Lawrence M, Kahaly George, Divers Jasmin, D'Agostino Ralph B, Imperatore Giuseppina, Dabelea Dana, Marcovina Santica, Black Mary Helen, Pihoker Catherine, Hasham Alia, Hammerstad Sara Salehi, Greenberg David A, Lotay Vaneet, Zhang Weijia, Monti Maria Cristina, Matheis Nina
Abstract excerpt
Autoimmune thyroid diseases (AITD) and Type 1 diabetes (T1D) frequently occur in the same individual pointing to a strong shared genetic susceptibility. Indeed, the co-occurrence of T1D and AITD in the same individual is classified as a variant of the autoimmune polyglandular syndrome type 3 (designated APS3v). Our aim was to identify new genes and mechanisms causing the co-occurrence of T1D + AITD (APS3v) in the...
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