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Article

Phenotype and prognostic correlations of the converter region mutations affecting the β myosin heavy chain.

Heart (British Cardiac Society) - 1 Jul 2015

García-Giustiniani Diego, Arad Michael, Ortíz-Genga Martín, Barriales-Villa Roberto, Fernández Xusto, Rodríguez-García Isabel, Mazzanti Andrea, Veira Elena, Maneiro Emilia, Rebolo Paula, Lesende Iván, Cazón Laura, Freimark Dov, Gimeno-Blanes Juan Ramón, Seidman Christine, Seidman Jonathan, McKenna William, Monserrat Lorenzo

Abstract excerpt

OBJECTIVES: The prognostic value of genetic studies in cardiomyopathies is still controversial. Our objective was to evaluate the outcome of patients with cardiomyopathy with mutations in the converter domain of β myosin heavy chain (MYH7). METHODS: Clinical characteristics and survival of 117 affected members with mutations in the converter domain of MYH7 were compared with 409 patients described in the...

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Source

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Identifiers

PMID: 25935763
DOI: 10.1136/heartjnl-2014-307205
PMCID: PMC4484257

Genes

MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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