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Article

Bacterial Cooperation Causes Systematic Errors in Pathogen Risk Assessment due to the Failure of the Independent Action Hypothesis.

PLoS pathogens - 1 Apr 2015

Cornforth Daniel M, Matthews Andrew, Brown Sam P, Raymond Ben

Abstract excerpt

The Independent Action Hypothesis (IAH) states that pathogenic individuals (cells, spores, virus particles etc.) behave independently of each other, so that each has an independent probability of causing systemic infection or death. The IAH is not just of basic scientific interest; it forms the basis of our current estimates of infectious disease risk in humans. Despite the important role of the IAH in managing...

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PMID: 25909384
DOI: 10.1371/journal.ppat.1004775
PMCID: PMC4409216

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