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Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence

18 Jun 2025

Abstract excerpt

Understanding the drivers and mechanisms of virulence evolution is still a major goal of evolutionary biologists and epidemiologists. Theory predicts that the way virulence evolves depends on the balance between the benefits and costs it provides to pathogen fitness. Additionally, host responses to infections, such as resistance or tolerance, play a critical role in shaping virulence evolution. But, while the...

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PMID: 40532126
DOI: 10.1371/journal.ppat.1012839

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