Article
Current insights into thrombotic microangiopathies: Thrombotic thrombocytopenic purpura and pregnancy.
Thrombosis research - 1 Feb 2015
von Auer Charis, von Krogh Anne-Sophie, Kremer Hovinga Johanna A, Lämmle Bernhard
Abstract excerpt
The complex relation between thrombotic thrombocytopenic purpura (TTP) and pregnancy is concisely reviewed. Pregnancy is a very strong trigger for acute disease manifestation in patients with hereditary TTP caused by double heterozygous or homozygous mutations of ADAMTS13 (ADisintegrin And Metalloprotease with ThromboSpondin type 1 domains, no. 13). In several affected women disease onset during their first...
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