Article
Left ventricular systolic dysfunction in asymptomatic Marfan syndrome patients is related to the severity of gene mutation: insights from the novel three dimensional speckle tracking echocardiography.
PloS one - 1 Jan 2015
Abd El Rahman Mohamed, Haase Denise, Rentzsch Axel, Olchvary Julia, Schäfers Hans-Joachim, Henn Wolfram, Wagenpfeil Stefan, Abdul-Khaliq Hashim
Abstract excerpt
BACKGROUND: In asymptomatic Marfan syndrome (MFS) patients we evaluated the relationship between the types of fibrillin-1 (FBN1) gene mutation and possible altered left ventricular (LV) function as assessed by three-dimensional speckle tracking echocardiography (3D-STE). METHODS AND RESULTS: Fort...
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