The effect of metallothionein 2A core promoter region single-nucleotide polymorphism on accumulation of toxic metals in sinonasal inverted papilloma tissues.

doi:10.1016/j.taap.2015.04.008

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Article

The effect of metallothionein 2A core promoter region single-nucleotide polymorphism on accumulation of toxic metals in sinonasal inverted papilloma tissues.

Toxicology and applied pharmacology - 15 Jun 2015

Starska Katarzyna, Bryś Magdalena, Forma Ewa, Olszewski Jurek, Pietkiewicz Piotr, Lewy-Trenda Iwona, Danilewicz Marian, Krześlak Anna

Abstract excerpt

Metallothioneins (MTs) are intracellular thiol-rich heavy metal-binding proteins which join trace metal ions protecting cells against heavy metal toxicity and regulate metal distribution and donation to various enzymes and transcription factors. The goal of this study was to identify the -5 A/G (rs28366003) single-nucleotide polymorphism (SNP) in the core promoter region of the MT2A gene, and to investigate its...

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PMID: 25900616
DOI: 10.1016/j.taap.2015.04.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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