Article
Rare missense variants within a single gene form yin yang haplotypes.
European journal of human genetics : EJHG - 1 Jan 2016
Curtis David
Abstract excerpt
Yin yang haplotype pairs differ at every SNP. They would not be accounted for by population models that incorporate sequential mutation, with or without recombination. Previous reports have claimed that there is a tendency for common SNPs to form yin yang haplotypes more often than would be expec...
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