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Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum

20 Apr 2015

Abstract excerpt

Syphilis is a globally occurring venereal disease, and its infection is propagated through sexual contact. The causative agent of syphilis, Treponema pallidum ssp. pallidum, a Gram-negative sphirochaete, is an obligate human parasite. Genome of T. pallidum ssp. pallidum SS14 strain (RefSeq NC_010741.1) encodes 1,027 proteins, of which 444 proteins are known as hypothetical proteins (HPs), i.e., proteins of...

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PMID: 25894582
DOI: 10.1371/journal.pone.0124177

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