Article
Dysregulated COL3A1 and RPL8, RPS16, and RPS23 in Disc Degeneration Revealed by Bioinformatics Methods.
Spine - 1 Jul 2015
Yang Zongde, Chen Xin, Zhang Qiulin, Cai Bin, Chen Kai, Chen Ziqiang, Bai Yushu, Shi Zhicai, Li Ming
Abstract excerpt
STUDY DESIGN: Bioinformatics analysis of published microarray data. OBJECTIVE: This study aimed to reveal the possible genes and pathways related to the pathogenesis of disc degeneration (DD) by analyzing the microarray data. SUMMARY OF BACKGROUND DATA: DD is one of the main causes of low back pain, which has become an enormous economic burden for society. METHODS: Gene expression data of annulus cells and...
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