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Article

Immediate suppression of seizure clusters by corticosteroids in PCDH19 female epilepsy.

Seizure - 1 Apr 2015

Higurashi Norimichi, Takahashi Yukitoshi, Kashimada Ayako, Sugawara Yuji, Sakuma Hiroshi, Tomonoh Yuko, Inoue Takahito, Hoshina Megumi, Satomi Ruri, Ohfu Masaharu, Itomi Kazuya, Takano Kyoko, Kirino Tomoko, Hirose Shinichi

Abstract excerpt

PURPOSE: The pathomechanism and treatment of PCDH19 female epilepsy (PCDH19-FE) remain unclear. Here, we report that corticosteroids are effective for control of the seizure clusters or other acute symptoms of PCDH19-FE and argue for the possible involvement of a compromised blood-brain barrier (BBB) in its pathogenesis. METHODS: The efficacy of corticosteroids was retrospectively reviewed in five Japanese...

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Source

Identifiers

PMID: 25891919
DOI: 10.1016/j.seizure.2015.02.006

Genes

PCDH19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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