Article
Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus
15 Apr 2015
Abstract excerpt
Middle East respiratory syndrome (MERS) is an emerging infectious disease caused by MERS coronavirus (MERS-CoV). The continuous increase of MERS cases has posed a serious threat to public health worldwide, calling for development of safe and effective MERS vaccines. We have previously shown that a recombinant protein containing residues 377-588 of MERS-CoV receptor-binding domain (RBD) fused with human Fc...
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