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Article

TGF-β signalling prevents pancreatic beta cell death after proliferation.

Cell proliferation - 1 Jun 2015

Lei Chen, Zhou Xiaoling, Pang Yi, Mao Yuanyuan, Lu Xixuan, Li Meijuan, Zhang Jie

Abstract excerpt

OBJECTIVES: Maintenance of functional beta cell mass is critical for prevention of diabetes. The transforming growth factor-beta (TGF-β) receptor signalling pathway plays an essential role in pancreatic development. However, its involvement in control of post-natal beta cell growth has only been recently reported. MATERIALS AND METHODS: Here, we studied the role of TGF-β receptor signalling in beta cell...

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Identifiers

PMID: 25871744
DOI: 10.1111/cpr.12183
PMCID: PMC6496026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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