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Article

External ear anomalies and hearing impairment in Noonan Syndrome.

International journal of pediatric otorhinolaryngology - 1 Jun 2015

van Trier Dorothée C, van Nierop Josephine, Draaisma Jos M Th, van der Burgt Ineke, Kunst Henricus, Croonen Ellen A, Admiraal Ronald J C

Abstract excerpt

OBJECTIVE: This is the first cohort in which hearing impairment and external ear anomalies in Noonan Syndrome are described extensively. METHODS: Retrospective analysis of the otorhinolaryngological and clinical genetic data from 97 Noonan Syndrome (NS) patients. Forty-four NS patients were seen by an otorhinolaryngologist for the analysis of hearing impairment. In our cohort 80 of the 97 patients were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25862627
DOI: 10.1016/j.ijporl.2015.03.021

Genes

PTPN11
KRAS
RAF1
SOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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