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Generating a self-organizing kidney from pluripotent cells

18 Feb 2015

Abstract excerpt

PURPOSE OF REVIEW: Recent studies on the directed differentiation of human pluripotent stem cells report tissue self-organization in vitro such that multiple component cell types arise in concert and arrange with respect to each, thereby recapitulating the morphogenetic events typical for that organ. Such self-organization has generated pituitary, optic cup, liver, brain, intestine, stomach and now kidney. Here,...

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PMID: 25856180
DOI: 10.1097/mot.0000000000000174

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