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Article

Complexities of Genetic Counseling for ALS: A Case of Two Siblings with Discordant Genetic Test Results.

Journal of genetic counseling - 1 Aug 2015

Mandich Paola, Mantero Vittorio, Verdiani Simonetta, Gotta Fabio, Caponnetto Claudia, Bellone Emilia, Ferrandes Giovanna, Origone Paola

Abstract excerpt

Rapid advances in the genetics of amyotrophic lateral sclerosis (ALS) have dramatically changed the approach of clinicians and researchers to the motor neuron diseases. We report two siblings in whom the genetic study provided conflicting results, hence raising a number of issues which deserve to be considered by clinicians involved in genetic testing for ALS. The first patient died within 2 years of ALS onset,...

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PMID: 25843563
DOI: 10.1007/s10897-015-9831-y

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TARDBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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