Article
Understanding type 2 diabetes: from genetics to epigenetics.
Acta diabetologica - 1 Oct 2015
Raciti Gregory Alexander, Longo Michele, Parrillo Luca, Ciccarelli Marco, Mirra Paola, Ungaro Paola, Formisano Pietro, Miele Claudia, Béguinot Francesco
Abstract excerpt
The known genetic variability (common DNA polymorphisms) does not account either for the current epidemics of type 2 diabetes or for the family transmission of this disorder. However, clinical, epidemiological and, more recently, experimental evidence indicates that environmental factors have an extraordinary impact on the natural history of type 2 diabetes. Some of these environmental hits are often shared in...
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