Article
Risk of Neoplasia in Pediatric Patients Receiving Growth Hormone Therapy--A Report From the Pediatric Endocrine Society Drug and Therapeutics Committee.
The Journal of clinical endocrinology and metabolism - 1 Jun 2015
Raman Sripriya, Grimberg Adda, Waguespack Steven G, Miller Bradley S, Sklar Charles A, Meacham Lillian R, Patterson Briana C
Abstract excerpt
CONTEXT: GH and IGF-1 have been shown to affect tumor growth in vitro and in some animal models. This report summarizes the available evidence on whether GH therapy in childhood is associated with an increased risk of neoplasia during treatment or after treatment is completed. EVIDENCE ACQUISITION: A PubMed search conducted through February 2014 retrieved original articles written in English addressing GH therapy...
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