Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics

Abstract excerpt

Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts. Different herpesviruses have different cell tropisms, and have been detected in a diverse range of tissues and sample types. Metagenomics-encompassing viromics-analyses the nucleic acid of a tissue or other sample in an unbiased manner, making few...

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