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Article

Severity of influenza A(H1N1) illness and emergence of D225G variant, 2013-14 influenza season, Florida, USA.

Emerging infectious diseases - 1 Apr 2015

Iovine Nicole M, Morris J Glenn, Fredenburg Kristianna, Rand Kenneth, Alnuaimat Hassan, Lipori Gloria, Brew Joseph, Lednicky John A

Abstract excerpt

Despite a regional decline in influenza A(H1N1)pdm09 virus infections during 2013-14, cases at a Florida hospital were more severe than those during 2009-10. Examined strains had a hemagglutinin polymorphism associated with enhanced binding to lower respiratory tract receptors. Genetic changes in this virus must be monitored to predict the effect of future pandemic viruses.

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Identifiers

PMID: 25811540
DOI: 10.3201/eid2104.141375
PMCID: PMC4378462

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