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Parental age affects somatic mutation rates in the progeny of flowering plants.

Plant physiology - 1 May 2015

Singh Amit Kumar, Bashir Tufail, Sailer Christian, Gurumoorthy Viswanathan, Ramakrishnan Anantha Maharasi, Dhanapal Shanmuhapreya, Grossniklaus Ueli, Baskar Ramamurthy

Abstract excerpt

In humans, it is well known that the parental reproductive age has a strong influence on mutations transmitted to their progeny. Meiotic nondisjunction is known to increase in older mothers, and base substitutions tend to go up with paternal reproductive age. Hence, it is clear that the germinal mutation rates are a function of both maternal and paternal ages in humans. In contrast, it is unknown whether the...

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PMID: 25810093
DOI: 10.1104/pp.15.00291
PMCID: PMC4424033

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