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Article

A novel approach for the detection and genetic analysis of live melanoma circulating tumor cells.

PloS one - 1 Jan 2015

Xu Melody J, Cooke Mariana, Steinmetz David, Karakousis Giorgos, Saxena Deeksha, Bartlett Edmund, Xu Xiaowei, Hahn Stephen M, Dorsey Jay F, Kao Gary D

Abstract excerpt

BACKGROUND: Circulating tumor cell (CTC) detection and genetic analysis may complement currently available disease assessments in patients with melanoma to improve risk stratification and monitoring. We therefore sought to establish the feasibility of a telomerase-based assay for detecting and isolating live melanoma CTCs. METHODS: The telomerase-based CTC assay utilizes an adenoviral vector that, in the presence...

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Identifiers

PMID: 25807549
DOI: 10.1371/journal.pone.0123376
PMCID: PMC4373770

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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