Article
Analysis of pharmacogenomic variants associated with population differentiation.
PloS one - 1 Jan 2015
Yeon Bora, Ahn Eunyong, Kim Kyung-Im, Kim In-Wha, Oh Jung Mi, Park Taesung
Abstract excerpt
In the present study, we systematically investigated population differentiation of drug-related (DR) genes in order to identify common genetic features underlying population-specific responses to drugs. To do so, we used the International HapMap project release 27 Data and Pharmacogenomics Knowledge Base (PharmGKB) database. First, we compared four measures for assessing population differentiation: the chi-square...
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