Article
Megakaryocytic emperipolesis and platelet function abnormalities in five patients with gray platelet syndrome.
Platelets - 1 Jan 2015
Larocca Luigi M, Heller Paula G, Podda Gianmarco, Pujol-Moix Nuria, Glembotsky Ana C, Pecci Alessandro, Alberelli Maria Adele, Balduini Carlo L, Landolfi Raffaele, Cattaneo Marco, De Candia Erica
Abstract excerpt
The gray platelet syndrome (GPS) is a rare congenital platelet disorder characterized by mild to moderate bleeding diathesis, macrothrombocytopenia and lack of azurophilic α-granules in platelets. Some platelet and megakaryocyte (MK) abnormalities have been described, but confirmative studies of the defects in larger patient cohorts have not been undertaken. We studied platelet function and bone marrow (BM)...
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