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Article

MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers.

Neuron - 8 Apr 2015

Andzelm Milena M, Cherry Timothy J, Harmin David A, Boeke Annabel C, Lee Charlotte, Hemberg Martin, Pawlyk Basil, Malik Athar N, Flavell Steven W, Sandberg Michael A, Raviola Elio, Greenberg Michael E

Abstract excerpt

Organismal development requires the precise coordination of genetic programs to regulate cell fate and function. MEF2 transcription factors (TFs) play essential roles in this process but how these broadly expressed factors contribute to the generation of specific cell types during development is poorly understood. Here we show that despite being expressed in virtually all mammalian tissues, in the retina MEF2D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25801704
DOI: 10.1016/j.neuron.2015.02.038
PMCID: PMC4393375

Genes

CRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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