Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modification of the susceptibility of gram-negative rods producing ESβLS to β-lactams by the efflux phenomenon.

PloS one - 1 Jan 2015

Laudy Agnieszka E, Osińska Paula, Namysłowska Alicja, Zając Olga, Tyski Stefan

Abstract excerpt

The production of β-lactamases is the most important mechanism of Gram-negative rod resistance to β-lactams. Resistance to ceftazidime and cefepime in clinical isolates of Enterobacteriaceae (especially ESβL-positive E. coli and K. pneumoniae) and P. aeruginosa is life-threatening. However, all strains of the above mentioned species possess chromosomally encoded RND efflux pump systems in addition to β-lactamase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to beta-Lactam Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Lactamases

Share to Cephalosporins

Share to Gram-Negative Bacteria

Share to Microbial Sensitivity Tests

Share to Mutation

Share to Pseudomonas aeruginosa

Source

Open in PubMed Open full text

Identifiers

PMID: 25793625
DOI: 10.1371/journal.pone.0119997
PMCID: PMC4368753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modification of the susceptibility of gram-negative rods producing ESβLS to β-lactams by the efflux phenomenon.PMID 25793625Read ↗

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative BacteriaSemantic proximity Read ↗

Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosaSemantic proximity Read ↗

Multidrug Efflux Pumps in Gram-Negative Bacteria and Their Role in Antibiotic ResistanceSemantic proximity Read ↗

Contribution of efflux and mutations in fluoroquinolone susceptibility in MDR enterobacterial isolates: a quantitative and molecular study.Semantic proximity Read ↗

Outer membrane permeability of Pseudomonas aeruginosa through β-lactams: new evidence on the role of OprD and OpdP porins in antibiotic resistanceSemantic proximity Read ↗

Efflux-mediated Multidrug Resistance in Critical Gram-negative Bacteria and Natural Efflux Pump InhibitorsSemantic proximity Read ↗

Efflux Pump, the Masked Side of ß-Lactam Resistance in Klebsiella pneumoniae Clinical IsolatesSemantic proximity Read ↗

Membrane Permeability and Regulation of Drug “Influx and Efflux” in Enterobacterial PathogensSemantic proximity Read ↗

Antibiotic Resistance Caused by Gram‐Negative Multidrug Efflux PumpsSemantic proximity Read ↗

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategySemantic proximity Read ↗

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence.Semantic proximity Read ↗

MexXY Multidrug Efflux System Is More Frequently Overexpressed in Ciprofloxacin Resistant French Clinical Isolates Compared to Hospital Environment OnesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.