Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic studies of the susceptibility of classical and wild-derived inbred mouse strains to monkeypox virus.

Virology - 1 Jul 2015

Earl Patricia L, Americo Jeffrey L, Moss Bernard

Abstract excerpt

Previously, we screened 38 inbred mouse strains for susceptibility to monkeypox virus (MPXV) and focused on wild-derived CAST mice because of their extreme vulnerability. Here, we provide further analysis of inbred mouse strains. NZW/Lac and C58 mice exhibited more weight loss than other classical inbred strains but all survived intranasal challenges with 10(4) to 10(6)PFU of MPXV. Mice from three wild derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to CAST gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mice, Inbred C57BL

Share to Mice, Inbred Strains

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 25791934
DOI: 10.1016/j.virol.2015.02.048
PMCID: PMC4437815

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic studies of the susceptibility of classical and wild-derived inbred mouse strains to monkeypox virus.PMID 25791934Read ↗

Identification of Wild-Derived Inbred Mouse Strains Highly Susceptible to Monkeypox Virus Infection for Use as Small Animal ModelsSemantic proximity Read ↗

Comparison of West African and Congo Basin Monkeypox Viruses in BALB/c and C57BL/6 MiceSemantic proximity Read ↗

Lethal Monkeypox Virus Infection of CAST/EiJ Mice Is Associated with a Deficient Gamma Interferon ResponseSemantic proximity Read ↗

Neuroinvasive Flavivirus Pathogenesis Is Restricted by Host Genetic Factors in Collaborative Cross Mice, Independently of Oas1bSemantic proximity Read ↗

Host genetic variation in susceptibility to Punta Toro virus.Semantic proximity Read ↗

Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1bSemantic proximity Read ↗

Insufficient Innate Immunity Contributes to the Susceptibility of the Castaneous Mouse to Orthopoxvirus InfectionSemantic proximity Read ↗

Susceptibility of AKXD recombinant inbred mouse strains to lymphomas.Semantic proximity Read ↗

Differential resistance/susceptibility patterns to pneumovirus infection among inbred mouse strains.Semantic proximity Read ↗

[Differences in susceptibility to peripheral infection with Japanese encephalitis virus among inbred strains of mouse].Semantic proximity Read ↗

Genetic studies of flavivirus resistance in inbred strains derived from wild mice: evidence for a new resistance allele at the flavivirus resistance locus (Flv).Semantic proximity Read ↗

Susceptibility of inbred strains of mice to murine AIDS (MAIDS) correlates with target cell expansion and high expression of defective MAIDS virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.