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Article

Evaluation of the contribution of the EYA4 and GRHL2 genes in Korean patients with autosomal dominant non-syndromic hearing loss.

PloS one - 1 Jan 2015

Kim Ye-Ri, Kim Min-A, Sagong Borum, Bae Seung-Hyun, Lee Hyo-Jeong, Kim Hyung-Jong, Choi Jae Young, Lee Kyu-Yup, Kim Un-Kyung

Abstract excerpt

EYA4 and GRHL2 encode transcription factors that play an important role in regulating many developmental stages. Since EYA4 and GRHL2 were identified as the transcription factors for the DFNA10 and DFNA28, 8 EYA4 mutations and 2 GRHL2 mutations have been reported worldwide. However, these genes have been reported in few studies of the Korean population. In this study, we performed a genetic analysis of EYA4 and...

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Source

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Identifiers

PMID: 25781927
DOI: 10.1371/journal.pone.0119443
PMCID: PMC4363478

Genes

GRHL2
EYA4
SIX3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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