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Article

Sera from children with autism induce autistic features which can be rescued with a CNTF small peptide mimetic in rats.

PloS one - 1 Jan 2015

Kazim Syed Faraz, Cardenas-Aguayo Maria Del Carmen, Arif Mohammad, Blanchard Julie, Fayyaz Fatima, Grundke-Iqbal Inge, Iqbal Khalid

Abstract excerpt

Autism is a neurodevelopmental disorder characterized clinically by impairments in social interaction and verbal and non-verbal communication skills as well as restricted interests and repetitive behavior. It has been hypothesized that altered brain environment including an imbalance in neurotrophic support during early development contributes to the pathophysiology of autism. Here we report that sera from...

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Source

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Identifiers

PMID: 25769033
DOI: 10.1371/journal.pone.0118627
PMCID: PMC4359103

Genes

CNTF
BDNF
LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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