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Article

Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2015

Ren Yinshi, Han Xianglong, Ho Sunita P, Harris Stephen E, Cao Zhengguo, Economides Aris N, Qin Chunlin, Ke Huazhu, Liu Min, Feng Jian Q

Abstract excerpt

Understanding periodontal ligament (PDL) biology and developing an effective treatment for bone and PDL damage due to periodontitis have been long-standing aims in dental medicine. Here, we first demonstrated by cell lineage tracing and mineral double-labeling approaches that murine PDL progenito...

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Share to Alveolar Bone Loss
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intercellular Signaling Peptides and Proteins

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Source

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Identifiers

PMID: 25757567
DOI: 10.1096/fj.14-265496
PMCID: PMC4478802

Genes

SOST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25757567-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model.PMID 25757567Read ↗

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