Article
Characteristics of refractory gastroesophageal reflux disease (GERD) symptoms -is switching proton pump inhibitors based on the patient's CYP2C19 genotype an effective management strategy?
Internal medicine (Tokyo, Japan) - 1 Jan 2015
Takeuchi Toshihisa, Oota Kazuhiro, Harada Satoshi, Edogawa Shoko, Kojima Yuichi, Sanomura Makoto, Sakaguchi Masahiro, Hayashi Katsuyoshi, Hongoh Yasushi, Itabashi Tsukasa, Kitae Hidehiro, Hoshimoto Masahiro, Takeuchi Nozomi, Higuchi Kazuhide
Abstract excerpt
OBJECTIVE: We investigated factors related to proton pump inhibitor (PPI) -refractory gastroesophageal reflux disease (GERD) symptoms, particularly with respect to acid, the CYP2C19 genotype and psychological aspects. METHODS: Patients with an Frequency Scale for the Symptoms of GERD (FSSG) score...
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