Article
Cadherin-13 gene is associated with hyperactive/impulsive symptoms in attention/deficit hyperactivity disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2015
Salatino-Oliveira Angélica, Genro Julia Pasqualini, Polanczyk Guilherme, Zeni Cristian, Schmitz Marcelo, Kieling Christian, Anselmi Luciana, Menezes Ana Maria Baptista, Barros Fernando Cde, Polina Evelise Regina, Mota Nina R, Grevet Eugênio Horácio, Bau Claiton Henrique Dotto, Rohde Luis Augusto, Hutz Mara Helena
Abstract excerpt
Several efforts have been made to find new genetic risk variants which explain the high heritability of ADHD. At the genome level, genes involved in neurodevelopmental pathways were pointed as candidates. CDH13 and CTNNA2 genes are within GWAS top hits in ADHD and there are emerging notions about their contribution to ADHD pathophysiology. The main goal of this study is to test the association between SNPs in...
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