Article
[Analysis of polymorphisms of genes associated with immune response and tissue remodeling in occupational chronic bronchitis].
Genetika - 1 Nov 2014
Akhmadishina L Z, Korytina G F, Kochetova O V, Viktorova E V, Viktorova T V
Abstract excerpt
The involvement of polymorphisms of genes encoding immune response-associated molecules (LTA, TNFA, ILB, ILRN, IL8, IL10, VDBP), matrix metalloproteinases (MMP1, MMP2, MMP3, MMP9, MMP12, ADAM33), and tissue and serum inhibitors of proteases (TIMP2, TIMP3, SERPINA1, SERPINA3) in the predisposition to occupational chronic bronchitis was assessed by PCR-RFLP analysis in groups of patients (n = 122) and healthy...
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