Article
Long-term efficacy of a hepatitis E vaccine.
The New England journal of medicine - 5 Mar 2015
Zhang Jun, Zhang Xue-Feng, Huang Shou-Jie, Wu Ting, Hu Yue-Mei, Wang Zhong-Ze, Wang Hua, Jiang Han-Min, Wang Yi-Jun, Yan Qiang, Guo Meng, Liu Xiao-Hui, Li Jing-Xin, Yang Chang-Lin, Tang Quan, Jiang Ren-Jie, Pan Hui-Rong, Li Yi-Min, Shih J Wai-Kuo, Ng Mun-Hon, Zhu Feng-Cai, Xia Ning-Shao
Abstract excerpt
BACKGROUND: Hepatitis E virus (HEV) is a leading cause of acute hepatitis. The long-term efficacy of a hepatitis E vaccine needs to be determined. METHODS: In an initial efficacy study, we randomly assigned healthy adults 16 to 65 years of age to receive three doses of either a hepatitis E vaccine (vaccine group; 56,302 participants) or a hepatitis B vaccine (control group; 56,302 participants). The vaccines were...
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