Article
Genetic variability of Candida albicans Sap8 propeptide in isolates from different types of infection.
BioMed research international - 1 Jan 2015
Carvalho-Pereira Joana, Vaz Catarina, Carneiro Catarina, Pais Célia, Sampaio Paula
Abstract excerpt
The secreted aspartic proteases (Saps) are among the most studied virulence determinants in Candida albicans. These proteins are translated as pre-pro-enzymes consisting of a signal sequence followed by a propeptide and the mature enzyme. The propeptides of secreted proteinases are important for the correct processing, folding/secretion of the mature enzyme. In this study, the DNA sequences of C. albicans Saps...
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