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Tri-allelic pattern of short tandem repeats identifies the murderer among identical twins and suggests an embryonic mutational origin.

Forensic science international. Genetics - 1 May 2015

Wang Li-Feng, Yang Ying, Zhang Xiao-Nan, Quan Xiao-Liang, Wu Yuan-Ming

Abstract excerpt

Monozygotic twins can be co-identified by genotyping of short tandem repeats (STRs); however, for distinguishing them, STR genotyping is ineffective, especially in the case of murder. Here, a rarely occurring tri-allelic pattern in the vWA locus (16, 18, 19) was identified only in the DNA of one identical twin, which could help to exonerate the innocent twin in a murder charge. This mutation was defined as...

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PMID: 25732248
DOI: 10.1016/j.fsigen.2015.01.010

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TCTA

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