Article
Bacteriophage Delivery by Nebulization and Efficacy Against Phenotypically Diverse Pseudomonas aeruginosa from Cystic Fibrosis Patients.
Journal of aerosol medicine and pulmonary drug delivery - 1 Oct 2015
Sahota Jaspreet Singh, Smith Claire Mary, Radhakrishnan Priya, Winstanley Craig, Goderdzishvili Marina, Chanishvili Nina, Kadioglu Aras, O'Callaghan Chris, Clokie Martha Rebecca Jane
Abstract excerpt
BACKGROUND: The rise in antibiotic-resistant Pseudomonas aeruginosa and the considerable difficulty in eradicating it from patients has re-motivated the study of bacteriophages as a therapeutic option. For this to be effective, host range and viability following nebulization need to be assessed. Host-range has not previously been assessed for the Liverpool Epidemic Strain (LES) isolates that are the most common...
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