Article
Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study.
Canadian journal of anaesthesia = Journal canadien d'anesthesie - 1 Apr 2015
Gradwohl Stephen C, Aranake Amrita, Abdallah Arbi Ben, McNair Paul, Lin Nan, Fritz Bradley A, Villafranca Alex, Glick David, Jacobsohn Eric, Mashour George A, Avidan Michael S
Abstract excerpt
PURPOSE: The red-hair phenotype, which is often produced by mutations in the melanocortin-1 receptor gene, has been associated with an increase in sedative, anesthetic, and analgesic requirements in both animal and human studies. Nevertheless, the clinical implications of this phenomenon in red-haired patients undergoing surgery are currently unknown. METHODS: In a secondary analysis of a prospective trial of...
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