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In Vitro Culture and Directed Osteogenic Differentiation of Human Pluripotent Stem Cells on Peptides-Decorated Two-Dimensional Microenvironment

11 Feb 2015

Abstract excerpt

Human pluripotent stem cells (hPSCs) are a promising cell source with pluripotency and capacity to differentiate into all human somatic cell types. Designing simple and safe biomaterials with an innate ability to induce osteoblastic lineage from hPSCs is desirable to realize their clinical adoption in bone regenerative medicine. To address the issue, here we developed a fully defined synthetic peptides-decorated...

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PMID: 25671246
DOI: 10.1021/acsami.5b00188

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