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Article

The phenotype spectrum of X-linked ichthyosis identified by chromosomal microarray.

Journal of the American Academy of Dermatology - 1 Apr 2015

Hand Jennifer L, Runke Cassandra K, Hodge Jennelle C

Abstract excerpt

BACKGROUND: Steroid sulfatase (STS) gene disruption causes X-linked ichthyosis (XLI). Interrogating the entire genome through chromosomal microarray (CMA), a test primarily used to screen patients with noncutaneous congenital anomalies, may detect STS deletions incidentally. OBJECTIVE: We sought to determine the variability of skin features associated with STS deletions diagnosed through CMA and to compare these...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25659225
DOI: 10.1016/j.jaad.2014.12.020

Genes

STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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