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Article

DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma

2 Feb 2015

Abstract excerpt

UNLABELLED: Epigenetic deregulation has emerged as a driver in human malignancies. There is no clear understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the potential role of DNA methylation markers as prognostic biomarkers. Analysis of tumor tissue from 304 patients with HCC treated with surgical resection allowed us to generate a methylation-based prognostic signature using a...

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PMID: 25645722
DOI: 10.1002/hep.27732

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