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The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology<i>In Vitro</i>

28 Jan 2015

Abstract excerpt

The telomerase reverse transcriptase protein TERT has recently been demonstrated to have a variety of functions both in vitro and in vivo, which are distinct from its canonical role in telomere extension. In different cellular systems, TERT protein has been shown to be protective through its interaction with mitochondria. TERT has previously been found in rodent neurons, and we hypothesize that it might have a...

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Share to Alzheimer's disease research and treatments
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 25632141
DOI: 10.1523/jneurosci.2925-14.2015

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