Article
The impact of rare variants in FUS in essential tremor.
Movement disorders : official journal of the Movement Disorder Society - 15 Apr 2015
Hopfner Franziska, Stevanin Giovanni, Müller Stefanie H, Mundwiller Emeline, Bungeroth May, Durr Alexandra, Pendziwiat Manuela, Anheim Mathieu, Schneider Susanne A, Tittmann Lukas, Klebe Stephan, Lorenz Delia, Deuschl Günther, Brice Alexis, Kuhlenbäumer Gregor
Abstract excerpt
OBJECTIVE: We analyzed the coding region of the Fused in Sarcoma (FUS) gene in familial essential tremor (ET) and reviewed previous studies assessing FUS variants in ET. BACKGROUND: ET is often a familial disorder with an autosomal dominant inheritance pattern. A potentially causative variant in FUS has been identified in one ET family. Subsequent studies described further putatively causal variants. METHODS: We...
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