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Article

Effect of mutation on aggregation propensity in homology model structures of syntaxin-3 from Homo sapiens.

Indian journal of biochemistry & biophysics - 1 Oct 2014

Maheshwari Amutha Selvaraj, Rajesh Durairaj, Padmanabhan Parasuraman, Archunan Govindaraju

Abstract excerpt

Perception of molecular mechanism would provide potent additional knowledge on mammalian membrane proteins involved in causing diseases. In human, syntaxin-3 (STX3) is a significant apical targeting protein in the epithelial membrane and in exocytosis process; it also acts as a vesicle transporter by cellular receptor in neutrophils, which is crucial for protein trafficking event. Structurally, syntaxin-3 has...

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PMID: 25630102

Genes

STX3

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