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Article

Novel linear polymers able to inhibit bacterial quorum sensing.

Macromolecular bioscience - 1 May 2015

Cavaleiro Eliana, Duarte Ana Sofia, Esteves Ana Cristina, Correia António, Whitcombe Michael J, Piletska Elena V, Piletsky Sergey A, Chianella Iva

Abstract excerpt

Bacterial phenotypes, such as biofilm formation, antibiotic resistance and virulence expression, are associated with quorum sensing. Quorum sensing is a density-dependent regulatory system of gene expression controlled by specific signal molecules, such as N-acyl homoserine lactones (AHLs), produced and released by bacteria. This study reports the development of linear polymers capable to attenuate quorum sensing...

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PMID: 25626858
DOI: 10.1002/mabi.201400447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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