N-Phenylacetanoyl- l -Homoserine Lactones Can Strongly Antagonize or Superagonize Quorum Sensing in Vibrio fischeri

Abstract excerpt

Bacteria monitor their population densities using low-molecular-weight ligands in a process known as quorum sensing. At sufficient cell densities, bacteria can change their mode of growth and behave as multicellular communities that play critical roles in both beneficial symbioses and the pathogenesis of infectious disease. The development of non-native ligands that can block quorum-sensing signals has emerged as...

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