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Metatranscriptomics reveals overall active bacterial composition in caries lesions

1 Jan 2014

Abstract excerpt

BACKGROUND: Identifying the microbial species in caries lesions is instrumental to determine the etiology of dental caries. However, a significant proportion of bacteria in carious lesions have not been cultured, and the use of molecular methods has been limited to DNA-based approaches, which detect both active and inactive or dead microorganisms. OBJECTIVE: To identify the RNA-based, metabolically active...

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PMID: 25626770
DOI: 10.3402/jom.v6.25443

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