Analysis of oral microbial dysbiosis associated with early childhood caries

Abstract excerpt

BACKGROUND: "Core microbes" play a key role in the development of caries and lead to microbial disorders. Our goal was to detect the core microbes associated with the microbiota imbalance in early childhood caries (ECC). METHODS: Fifteen caries-free children and fifteen high-caries (DMFT ≥ 10) children aged 4-6 years old were recruited according to the diagnostic criteria of caries suggested by the WHO. The 16S...

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