[Abnormalities of signal transduction molecules in multiple myeloma].

Article

[Abnormalities of signal transduction molecules in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jan 2015

Sasaki Makoto, Komatsu Norio

Abstract excerpt

Although the recent advances in therapeutic drugs have improved outcomes for multiple myeloma, this disease remains incurable. One of the most commonly detected genetic abnormalities in myeloma is the activating oncogenic mutation of KRAS and NRAS in MAP kinase pathway. New technologies, such as...

Topics

Clinical Trials as Topic
High-Throughput Nucleotide Sequencing
Humans
Multiple Myeloma
Mutation
Proto-Oncogene Proteins B-raf
Signal Transduction

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